SV40 TAg mouse models of cancer
作者： Emily K. Colvin , Chris Weir , Rowan J. Ikin , Amanda L. Hudson
DOI: 10.1016/J.SEMCDB.2014.02.004
关键词: Biology 、 Immunology 、 Human cancer 、 Transgene 、 Cancer 、 Sv40 tag 、 Carcinogenesis 、 Computational biology 、 Sv40 virus
摘要: The discovery of a number viruses with the ability to induce tumours in animals and transform human cells has vastly impacted cancer research. Much what is known about tumorigenesis today regarding tumour drivers suppressors been discovered through experiments using viruses. SV40 virus proven extremely successful generating transgenic models many types this review provides an overview these seeks give evidence as their relevance modern era personalised medicine technological advancements.
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