Impact of prostate cancer testing: an evaluation of the emotional consequences of a negative biopsy result.

摘要: When testing for prostate cancer, as many 75% of men with a raised prostate-specific antigen (PSA) have benign biopsy result. Little is known about the psychological effect this result these men. In all, 330 participating in cancer and treatment (ProtecT) study were studied; aged 50–69 years PSA level ⩾3 ng ml−1 negative Distress mood measured at four time-points: two during diagnostic after The majority not greatly affected by or impact on health was highest time biopsy, around 20% reporting high distress (33 out 171) tense/anxious moods (35 180). Longitudinal analysis 195 showed significant increase compared levels test (difference Impact Events Scale (IES) score: 9.47; 95% confidence interval (CI) (6.97, 12.12); P<0.001). These remained elevated immediately 7.32; CI (5.51, 9.52); P<0.001) 12 weeks later 2.42; (0.50, 1.15); P=0.009). Psychological predicted anxiety subsequent time-points. Most coped well process, although minority experienced Men should be informed risk relating to uncertainty before they consent testing.