Childhood-onset obsessive-compulsive disorder: a tic-related subtype of OCD?

摘要: Obsessive-compulsive disorder (OCD) is a psychiatric condition characterized by recurrent obsessions or compulsions that cause significant impairment distress. Although OCD was once perceived to be relatively rare in childhood, current estimates suggest as many half of all adult cases may have their onset childhood adolescence. In general, there appears great deal continuity between the clinical presentation children and adults. Yet, numerous differences also been found child OCD, including sex distribution, patterns comorbidity, degree familial loading. These raise issue whether obsessive-compulsive symptoms but perhaps persist into life, are meaningfully different from those emerge de novo adulthood. this article, research on child- adult-onset critically reviewed. It proposed child-onset represents phenomenologically etiologically distinct subtype bearing close genetic relationship tic-disorders possibly sharing common similar pathogenesis. Clinical implications versus distinction discussed.