Rhabdomyolysis: a review of the literature

作者: P.J.E. Poels , F.J.M. Gabreëls

DOI: 10.1016/0303-8467(93)90122-W

关键词: Skeletal muscleBioinformaticsRhabdomyolysisFulminantDifferential diagnosismyalgiaPathologyMyoglobinuriaEtiologyMedicinePathophysiology

摘要: Rhabdomyolysis (lysis of skeletal muscle cells) is a potentially lethal syndrome with broad spectrum clinical and biochemical findings. Myalgia, pigmenturia elevated activity serum creatine kinase are the common features. Fulminant rhabdomyolysis may be associated severe metabolic disturbances involvement other organ systems. Cardiac arrest, compartment acute renal failure major complications. The extent life-threatening complications strongly depends on early diagnosis adequate therapy. As repair mechanism striated functions very well, prognosis adequately treated excellent. This article reviews present state knowledge rhabdomyolysis, pathophysiologic background, classification etiological provocative factors.

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