AMINO-5-(5-MEMBERED)HETERO-ARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR beta-SECRETASE MODULATION
作者： Dominick Anthony Quagliato , Patrick Michael Andrae , William Ronald Solvibile , William Floyd Fobare , James Joseph Erdei
DOI:
关键词: Beta (finance) 、 Amyloid precursor protein secretase 、 Stereochemistry 、 Neuroscience 、 Chemistry
摘要: The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula I also methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits neurofibrillary tangles
google.com.ar参考文章(32)
James Joseph Erdei, Joseph Raymond Stock, Yinfa Yan, Iwan Suwandi Gunawan, Michael Sotirios Malamas, Pawel Nowak, Cycloalkyl amino-hydantoin compounds and use thereof for beta-secretase modulation ,(2006)
Dominick Anthony Quagliato, Patrick Michael Andrae, Yi Fan, Dihydrospiro[dibenzo[a,d][7]annulene-5,4'-imidazol] compounds for the inhibition of beta-secretase ,(2007)
William Ronald Solvibile, William Floyd Fobare, Substituted thienyl and furyl acylguanidines and methods of their use as beta-secretase modulators ,(2006)
Dominick Anthony Quagliato, Albert Jean Robichaud, Yanfang Li, Michael Sotirios Malamas, Ping Zhou, Amino-5-(6-membered)heteroarylimidazolone compounds and the use thereof for beta-secretase modulation ,(2006)
Eric Steven Manas, Yanfang Li, Yinfa Yan, Yi Fan, Pawel Wojciech Nowak, Derek Cecil Cole, Ronald Charles Bernotas, Ping Zhou, 2-AMINO-5-PIPERIDINYLIMIDAZOLONE COMPOUNDS AND USE THEREOF FOR β-SECRETASE MODULATION ,(2006)
Hiroyuki Setoi, Tatsuya Zenkoh, Kentaro Sato, Hirokazu Tanaka, Hitoshi Sawada, Takehiko Ohkawa, Benzamide derivatives and their use as vasopressin antagonists ,(1996)
Dominick A. Quagliato, Michael Sotirios Malamas, James Joseph Erdei, Yinfa Yan, Iwan Suwandi Gunawan, Ping Zhou, Amino-5,5-diphenylimidazolone derivatives for the inhibition of beta-secretase ,(2005)
Yu Hui, Keith Douglas Barnes, Iwan Suwandi Gunawan, Matthew Robert Johnson, Michael Sotirios Malamas, James Joseph Erdei, Diphenylimidazopyrimidine and -imidazole amines as inhibitors of b-secretase ,(2005)
Boyd Lynn Harrison, Iwan Suwandi Gunawan, Michael Sotirios Malamas, James Joseph Erdei, Pawel Wojciech Nowak, Amino-imidazolones for the inhibition of beta-secretase ,(2006)
Albert Jean Robichaud, Michael Sotirios Malamas, William Ronald Solvibile, Jeffrey Scott Condon, William Floyd Fobare, Frank Eldridge Lovering, Amino-pyridines as inhibitors of .beta.-secretase ,(2006)