Radiation induced DNA double strand breaks and chromosome aberrations.

作者: H. P. Leenhouts , K. H. Chadwick

DOI: 10.1007/BF00277015

关键词: Chromosome (genetic algorithm)DNAChromatidA-DNACell killingRadiobiologyBiophysicsBiologyChromosome aberrationProgrammed cell deathGenetics

摘要: This paper presents arguments which favour an alternative approach to the interpretation of radiation induced chromosome aberrations. Starting from modern concept that a has DNA double stranded helix backbone and induction strand breaks quadratic dose relationship, it is concluded most aberrations arise only one break. The direct correlation between cell death derived model demonstrated by analysis experimental results. effect rate, LET occurrence chromatid after irradiation in G1 are all logically explained theoretical model.

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