Solid variant of mammary adenoid cystic carcinoma with basaloid features: a study of nine cases.

作者: Sandra J. Shin , Paul Peter Rosen

DOI: 10.1097/00000478-200204000-00002

关键词: Adenoid cystic carcinomaPathologyImmunohistochemistryLymphMedicineCarcinomaLymph nodeNeoplasmMammary glandMastectomy

摘要: Adenoid cystic carcinoma of the breast is a rare neoplasm that represents 5 mitotic figures per 10 high power microscopic fields. Intercalated ducts were found in all tumors, being well formed six and poorly three. Immunohistochemical stains for cytokeratins, basement membranes, vimentin consistently positive. Surgery was performed cases consisting excision seven mastectomy two. Axillary lymph node metastases two axillary dissections four had negative nodes. The nodes not examined three patients. Follow-up information available Six women no evidence disease after follow-up 2-88 months (mean 32 months), one patient died unknown causes, lost to follow-up. It concluded solid variant mammary with basaloid features histologically distinct tumor capable metastases. Long-term larger series will be needed determine whether prognosis these patients differs significantly from conventional adenoid carcinoma. Presently, are candidates staging by sentinel mapping or low dissection if there clinical Systemic adjuvant treatment would prudent when nodal present. Breast-conserving surgery radiation an option margins can achieved because this appears unicentric form

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