EGF induces tyrosine phosphorylation of phospholipase C-II: A potential mechanism for EGF receptor signaling

作者: B. Margolis , S.G. Rhee , S. Felder , M. Mervic , R. Lyall

DOI: 10.1016/0092-8674(89)90047-0

关键词: Epidermal growth factorROR1Receptor tyrosine kinaseBiologyTyrosine phosphorylationTyrosineTropomyosin receptor kinase CMolecular biologyPhosphorylationTyrosine kinaseGeneral Biochemistry, Genetics and Molecular Biology

摘要: … with anti-EGF-R antibodies, we estimate that approximately 1% of EGF-R molecules are … of tyrphostin RG50864 on EGF-induced PLC-II phosphorylation and on EGF-induced Ca2+ …

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