Methods and compositions for inducing antigen-specific immune responses

作者: Debra Drane , Michael McCluskie , Heather Davis

DOI:

关键词: AntigenVirologyOligonucleotideImmunologyBiologyAntigen specificImmune systemImmune receptor

摘要: Vaccine compositions comprising (a) an oligonucleotide, (b) and immune stimulating complex (c) antigen induce a strong interferon-gamma response. Both oligonucleotides containing stimulatory motifs lacking contribute to response when administered with complex.

参考文章(47)
Jonathan Cebon, Weisan Chen, Ian Davis, Simon Green, In vivo efficacy of ny-eso-1 plus adjuvant ,(2004)
Robert L Bratzler, Arthur M Krieg, Stefan Bauer, Christian Schetter, Marion Jurk, Joerg Vollmer, Methods and products for enhancing immune responses using imidazoquinoline compounds ,(2002)
Kristian Dalsgaard, Nikolai Soeren Kirkby, Polynucleotide binding complexes comprising sterols and saponins ,(2002)
Bror Morein, Karin Lovgren Bengtsson, Jill Ekstrom, Iscom or iscom-matrix comprising hydrophobic receptor molecules for antigenic substances ,(1997)
Angela M. O'Sullivan, Neill M. MacKenzie, Formation of adjuvant complexes ,(1989)
Jennifer D. Tousignant, Nelson S. Yew, Hongmei Zhao, Seng H. Cheng, CpG reduced plasmids and viral vectors ,(2001)
John Cooper Cox, Debbie Pauline Drane, Andreas Suhrbier, Immunogenic complexes and methods relating thereto ,(2000)