[F-18] fluorodeoxyglucose positron emission tomography as a tool for early recognition of incomplete tumor destruction after radiofrequency ablation for liver metastases.

摘要: Background and Objectives To assess the value of FDG positron emission tomography (PET) for early detection incomplete tumor destruction after radiofrequency ablation (RFA) liver metastasis. Methods Twenty-eight unresectable metastases in 17 patients were treated by RFA. Patients underwent computed (CT) FDG-PET preoperatively, at 1 week, month, 3 months postoperatively. Postoperative CT week month analyzed to identify hypervascular hypermetabolic residual tumors RFA site. These results correlated with follow-up and, case reintervention, pathologic results. Results In 24/28 RFA-treated metastases, showed no residues. During follow-up, none these 13 developed local recurrence In four patients, peripheral residue RFA, whereas did not revealed tumor. three persistence viable cells was biopsy-proven reintervention. fourth, subsequent development a recurrence. Conclusions FDG-PET accurately monitors efficacy treatment as it recognizes ablation, detectable on CT. J. Surg. Oncol. 2003;84:215–223. © 2003 Wiley-Liss, Inc.