Plasma 25-hydroxyvitamin D levels in young children undergoing placement of tympanostomy tubes.

作者: Linda A. Linday , Richard D. Shindledecker , Jay N. Dolitsky , Tai C. Chen , Michael F. Holick

DOI: 10.1177/000348940811701006

关键词: PediatricsVitaminMedicineEicosapentaenoic acidRicketsAmbulatoryGastroenterologyInternal medicineVitamin D and neurology

摘要: OBJECTIVES We report the plasma 25-hydroxyvitamin D [25(OH)D] levels of 16 young children who were undergoing ambulatory surgery for placement tympanostomy tubes. METHODS previously obtained blood samples from and reported that they had lower than adults eicosapentaenoic acid (an omega-3 fatty acid), vitamin A, selenium. Plasma frozen continuously at -80 degrees C was available subjects RESULTS The mean (+/- SD) age patients 3.7 +/- 1.6 years (median, 2.9 years; range, 1.9 to 7.4 years). Sixty-two percent male; half white, Hispanic. private patients; parents taking supplements. None a history rickets. 25(OH)D less 10 ng/mL; 50% 20 ng/mL (deficient in adults); another 31% 21 29 (insufficient adults). CONCLUSIONS Vitamin is essential production endogenous antimicrobial peptides, has been linked seasonal, epidemic influenza A. However, level needed prevent infection with various human pathogens not defined. In view increasing bacterial resistance emerging new pathogens, further research on relationship other nutritional factors warranted.

参考文章(35)
Maija H. Zile, Elizabeth C. Bunge, Hector F. Deluca, DNA labeling of rat epithelial tissues in vitamin A deficiency. Journal of Nutrition. ,vol. 111, pp. 777- 788 ,(1981) , 10.1093/JN/111.5.777
Linda A Linday, Jay N Dolitsky, Richard D Shindledecker, Nutritional supplements as adjunctive therapy for children with chronic/recurrent sinusitis: pilot research. International Journal of Pediatric Otorhinolaryngology. ,vol. 68, pp. 785- 793 ,(2004) , 10.1016/J.IJPORL.2004.01.009
Susan S. Sullivan, Clifford J. Rosen, William A. Halteman, Tai C. Chen, Michael F. Holick, Adolescent Girls in Maine Are at Risk for Vitamin D Insufficiency Journal of The American Dietetic Association. ,vol. 105, pp. 971- 974 ,(2005) , 10.1016/J.JADA.2005.03.002
F Termorshuizen, Alet Wijga, Jorrit Gerritsen, HJ Neijens, Henk van Loveren, None, Exposure to solar ultraviolet radiation and respiratory tract symptoms in 1-year-old children. Photodermatology, Photoimmunology and Photomedicine. ,vol. 20, pp. 270- 271 ,(2004) , 10.1111/J.1600-0781.2004.00110.X
Shelley R. Kreiter, Robert P. Schwartz, Henry N. Kirkman, Philippa A. Charlton, Ali S. Calikoglu, Marsha L. Davenport, Nutritional rickets in African American breast-fed infants. The Journal of Pediatrics. ,vol. 137, pp. 153- 157 ,(2000) , 10.1067/MPD.2000.109009
Jürgen Schauber, Robert A. Dorschner, Alvin B. Coda, Amanda S. Büchau, Philip T. Liu, David Kiken, Yolanda R. Helfrich, Sewon Kang, Hashem Z. Elalieh, Andreas Steinmeyer, Ulrich Zügel, Daniel D. Bikle, Robert L. Modlin, Richard L. Gallo, Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D–dependent mechanism Journal of Clinical Investigation. ,vol. 117, pp. 803- 811 ,(2007) , 10.1172/JCI30142
Bradford D. Gessner, Julia Plotnik, Pam T. Muth, 25-hydroxyvitamin D levels among healthy children in Alaska. The Journal of Pediatrics. ,vol. 143, pp. 434- 437 ,(2003) , 10.1067/S0022-3476(03)00410-4
Francis W. Kemp, Prasad V.S.V. Neti, Roger W. Howell, Peter Wenger, Donald B. Louria, John D. Bogden, Elevated blood lead concentrations and vitamin D deficiency in winter and summer in young urban children. Environmental Health Perspectives. ,vol. 115, pp. 630- 635 ,(2006) , 10.1289/EHP.9389