Paraventricular lesions: hormonal and cardiovascular responses to hemorrhage.
作者： Daniel N. Darlington , Jeanette Shinsako , Mary F. Dallman
DOI: 10.1016/0006-8993(88)91486-2
关键词: Epinephrine 、 Phenylephrine 、 Baroreceptor 、 Lesion 、 Reflex 、 Norepinephrine (medication) 、 Anesthesia 、 Adrenocorticotropic hormone 、 Internal medicine 、 Endocrinology 、 Catecholamine 、 Medicine
摘要: The responses of adrenocorticotropin (ACTH), renin, epinephrine and norepinephrine arterial pressure heart rate (HR) to hypotensive hemorrhage were examined before 1 h after lesion the paraventricular nuclei (PVN) in pentobarbital-anesthetized rats day 4 days PVN conscious rats. ACTH response was abolished (n = 8) 14) whereas sham groups (in both anesthetized studies, n 8 16 respectively) remained intact. had no effect on basal levels lesion. epinephrine, mean blood (MABP) HR not affected or Resting above variables did change a small (but significant) baroreceptor reflex study (reflex changes caused by phenylephrine- nitroglycerin-induced MABP) study. group with lesions gained more weight 6 than lesions. We conclude that are part neural pathway involved regulation during perturbations cardiovascular system gain have little resting stimulated (hemorrhage) norepinephrine, MABP reflex.
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