EGFR gene gain and PTEN protein expression are favorable prognostic factors in patients with KRAS wild-type metastatic colorectal cancer treated with cetuximab
作者： Evangelia Razis , George Pentheroudakis , George Rigakos , Mattheos Bobos , George Kouvatseas
DOI: 10.1007/S00432-014-1626-2
关键词: Colorectal cancer 、 KRAS 、 Oncology 、 Cetuximab 、 Hematology 、 Internal medicine 、 Monoclonal 、 Epidermal growth factor receptor 、 Cancer research 、 PTEN 、 Antibody 、 Medicine
摘要: … In the present study, we assessed PTEN and EGFR status with immunohistochemistry (IHC) and FISH and their correlation with cetuximab treatment outcome in a much larger cohort, …
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