Impact of 3-dimensional bifurcation angle on 5-year outcome of patients after percutaneous coronary intervention for left main coronary artery disease: a substudy of the SYNTAX trial (synergy between percutaneous coronary intervention with taxus and cardiac surgery).

作者: Chrysafios Girasis , Vasim Farooq , Roberto Diletti , Takashi Muramatsu , Christos V. Bourantas

DOI: 10.1016/J.JCIN.2013.08.009

关键词: Internal medicineCardiac surgeryMyocardial infarctionArteryPercutaneous coronary interventionMedicineStentCardiologySurgeryDiastoleConventional PCICircumflex

摘要: Objectives This study sought to investigate the impact of left main coronary artery (LMCA) 3-dimensional (3D) bifurcation angle (BA) parameters on 5-year clinical outcomes patients randomized LMCA percutaneous intervention (PCI) in SYNTAX (Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery) trial. Background BA can affect outcome after PCI; 3D angiographic analysis provides reliable measurements. Methods The diastolic distal (between anterior descending circumflex) its systolic-diastolic range were explored. A stratified post-hoc survival was performed for major adverse cardiac cardiovascular events (MACCE) (all-cause death, cerebrovascular accident, myocardial infarction, or repeat revascularization), a safety endpoint infarction), revascularization. Analysis where available pre- post-PCI. Results Of 266 eligible analysis, 185 underwent PCI (group B); 1 stent used 75 B1), whereas ≥2 stents 110 B2). Stratification across pre-PCI tertiles ( Conclusions restricted post-procedural resulted higher event rates PCI. Pre-PCI value did not outcome.

参考文章(37)
Gaku Nakazawa, Saami K. Yazdani, Aloke V. Finn, Marc Vorpahl, Frank D. Kolodgie, Renu Virmani, Pathological Findings at Bifurcation Lesions Journal of the American College of Cardiology. ,vol. 55, pp. 1679- 1687 ,(2010) , 10.1016/J.JACC.2010.01.021
Yoshinobu Onuma, Chrysafios Girasis, Nicolo Piazza, Hector M Garcia-Garcia, Neville Kukreja, Scot Garg, Jannet Eindhoven, Jin-Ming Cheng, Marco Valgimigli, Ron van Domburg, Patrick W Serruys, Interventional Cardiologists at Thoraxcenter 2000–2005, Long-Term Clinical Results Following Stenting of the Left Main Stem: Insights From RESEARCH (Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital) and T-SEARCH (Taxus-Stent Evaluated at Rotterdam Cardiology Hospital) Registries Jacc-cardiovascular Interventions. ,vol. 3, pp. 584- 594 ,(2010) , 10.1016/J.JCIN.2010.03.017
Chrysafios Girasis, Patrick W. Serruys, Yoshinobu Onuma, Antonio Colombo, David R. Holmes, Ted E. Feldman, Eric J. Bass, Katrin Leadley, Keith D. Dawkins, Marie-Claude Morice, 3-Dimensional bifurcation angle analysis in patients with left main disease: a substudy of the SYNTAX trial (SYNergy Between Percutaneous Coronary Intervention with TAXus and Cardiac Surgery). Jacc-cardiovascular Interventions. ,vol. 3, pp. 41- 48 ,(2010) , 10.1016/J.JCIN.2009.10.019
Michail I. Papafaklis, Christos V. Bourantas, Panagiotis E. Theodorakis, Christos S. Katsouras, Katerina K. Naka, Dimitrios I. Fotiadis, Lampros K. Michalis, The Effect of Shear Stress on Neointimal Response Following Sirolimus- and Paclitaxel-Eluting Stent Implantation Compared With Bare-Metal Stents in Humans Jacc-cardiovascular Interventions. ,vol. 3, pp. 1181- 1189 ,(2010) , 10.1016/J.JCIN.2010.08.018
Yoshinobu Onuma, Chrysafios Girasis, Jean-Paul Aben, Giovanna Sarno, Nicolo Piazza, Coen Lokkerbol, Marie-Angel Morel, Patrick Serruys, A novel dedicated 3-dimensional quantitative coronary analysis methodology for bifurcation lesions. Eurointervention. ,vol. 7, pp. 629- 635 ,(2011) , 10.4244/EIJV7I5A100
Steffen Desch, Gerhard Schuler, Friedrich-Wilhelm Mohr, Enno Boudriot, Holger Thiele, Thomas Walther, Christoph Liebetrau, Peter Boeckstegers, Tilmann Pohl, Bruno Reichart, Harald Mudra, Florian Beier, Brigitte Gansera, Franz-Josef Neumann, Michael Gick, Thomas Zietak, Randomized Comparison of Percutaneous Coronary Intervention With Sirolimus-Eluting Stents Versus Coronary Artery Bypass Grafting in Unprotected Left Main Stem Stenosis Journal of the American College of Cardiology. ,vol. 57, pp. 538- 545 ,(2011) , 10.1016/J.JACC.2010.09.038
Vladimir Dzavik, Rajesh Kharbanda, Joan Ivanov, Douglas J. Ing, Sanh Bui, Karen Mackie, Rachael Ramsamujh, Alan Barolet, Leonard Schwartz, Peter H. Seidelin, Predictors of long-term outcome after crush stenting of coronary bifurcation lesions: importance of the bifurcation angle. American Heart Journal. ,vol. 152, pp. 762- 769 ,(2006) , 10.1016/J.AHJ.2006.04.033
John A. Ormiston, Mark W.I. Webster, Seifeddin El Jack, Peter N. Ruygrok, James T. Stewart, Douglas Scott, Erin Currie, Monique J. Panther, Bronwyn Shaw, Barbara O'Shaughnessy, Drug-eluting stents for coronary bifurcations: bench testing of provisional side-branch strategies. Catheterization and Cardiovascular Interventions. ,vol. 67, pp. 49- 55 ,(2006) , 10.1002/CCD.20453
Shaoliang Chen, Junjie Zhang, Fei Ye, Yundai Chen, Weiyi Fang, Meng Wei, Ben He, Xuewen Sun, Song Yang, Tak W. Kwan, Final kissing balloon inflation by classic crush stenting did not improve the clinical outcomes for the treatment of unprotected left main bifurcation lesions: the importance of double-kissing crush technique. Catheterization and Cardiovascular Interventions. ,vol. 71, pp. 166- 172 ,(2008) , 10.1002/CCD.21317
Wook-Sung Chung, Chul-Soo Park, Ki-Bae Seung, Pum-Joon Kim, Jong-Min Lee, Bon-Kwon Koo, Yang-Soo Jang, Joo-Young Yang, Jung-Han Yoon, Doo-Il Kim, Young-Won Yoon, Jong-Seon Park, Yoon-Haeng Cho, Seung-Jung Park, None, The incidence and clinical impact of stent strut fractures developed after drug-eluting stent implantation International Journal of Cardiology. ,vol. 125, pp. 325- 331 ,(2008) , 10.1016/J.IJCARD.2007.02.033