Central nervous system diseases : innovative animal models from lab to clinic

摘要: Part I. Aging and Alzheimer's Disease. The Cholinergic Hypothesis a Generation Later: Perspectives Gained on the Use Integration of Animal Models, Raymond T. Bartus. Patterns Cognitive Decline in Aged Rhesus Monkey, Mark B. Moss, Ronald J. Killiany, James G. Herndon. Lesions as Model Disease: Effects Nerve Growth Factor, M. Conner H. Tuszynski. Immunolesioned Transmitter Dysfunction, Gary L. Wenk. An Intracerebral Tumor Necrosis Factor-a Infusion for Inflammation Disease, Kimberly Bjugstad W. Arendash. Senescence-Accelerated Mouse Possible Senile Dementia, Yasuyuki Nomura, Yasunobu Okuma, Yoshihisa Kitamura. Transgenic Mice Overexpressing Presenilin cDNAs: Phenotype Utility Modeling Karen Duff. II. Parkinson's Intervention Strategies Degeneration Dopamine Neurons Parkinsonism: Optimizing Behavioral Assessment Outcome, Timothy Schallert Jennifer Tillerson. Development Outcome Measures Preclinical Research, D. Lindner. Unilateral Dopamine-Depleted Marmoset, E. Annett, R. Smyly, Henderson, Cummings, A. Kendall, S. Dunnett. Molecules Neuroprotection Regeneration Models O. Isacson, C. Costantini, Galpern. Antisense Knockdown Receptors, Simranjit Kaur Ian Creese. Is Trophic Factor Gene Disruption 'Knockout' Disease?, Ann-Charlotte Granholm Barry Hoffer. III. Huntington's Operant Analysis Striatal Peter Brasted, Mate Dobrossy, Dawn Eagle, Falguni Nathwani, Trevor Robbins, Stephen Intrastriatal Injections Quinolinic Acid Developing Neuroprotective Dwaine F.Emerich. Systemic Administration 3-Nitropropionic Acid: A New Disease Rat, Emmanuel Brouillet, Philippe Hantraye, Flint Beal. Replicating Huntington Disease's Nonhuman Primates, Stephane Palfi, Vincent Mittoux, Caroline Dautry, Francoise Conde, Brouillet. Gillian P. Bates, Laura Mangiarini, Davies. IV. Traumatic Brain Injury Stroke. Rigid Indentation Richard Sutton. Rodent Ischemia Embolism Ligation Middle Cerebral Artery: Clinical Relevance to Treatment Stroke, Cesario V. Borlongan, Hitoo Nishino, Yun Wang, Paul Sanberg. Primate Hypertensive Cerebrovascular Moss. Innovations Leading Therapy. Nictotinic Therapeutics Tourette Syndrome Other Neuropsychiatric Disorders: From Laboratory Clinic, Doug Shytle, Archie Silver, Mary Newman, Neural Grafting Ben Roitberg, Shin, Joseph Sramek, Jeffrey Kordower. Future Prospects Therapy Treating CNS Diseases, Daniel Peterson, Jasodhara Ray, Fred Gage. Index.