Sirtuins in Epigenetic Regulation
作者： Hui Jing , Hening Lin
DOI: 10.1021/CR500457H
关键词: Histone deacetylase 、 Biochemistry 、 Chromatin 、 Epigenetics 、 Sirtuin 、 Cell biology 、 Chemistry 、 SIR proteins 、 Histone H4 、 Histone 、 Acetylation
摘要: 1.1. Discovery of Sirtuins The founding member of sirtuin is the yeast-silencing information regulator 2 (SIR2) protein, one of four proteins (SIR1− 4) required for silencing the mating-…
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