Japanese guidelines for the management of acute pancreatitis: Japanese Guidelines 2015.

摘要: Background Japanese (JPN) guidelines for the management of acute pancreatitis were published in 2006. The severity assessment criteria later revised by Japanese Ministry Health, Labour and Welfare (MHLW) 2008, leading to their publication as JPN Guidelines 2010. Following 2012 revision Atlanta Classifications Acute Pancreatitis, which classifications regional complications revised, development a minimally invasive method local spread, emerging evidence was gathered into Guidelines. Methods A comprehensive evaluation carried out on epidemiology, diagnosis, severity, treatment, post-endoscopic retrograde cholangiopancreatography (ERCP) clinical indicators, based concepts GRADE system (Grading Recommendations Assessment, Development Evaluation). With graded recommendations, where unclear, Meta-Analysis team 2015 conducted an additional new meta-analysis, results included guidelines. Results Thirty-nine questions prepared 17 subject areas, 43 recommendations made. areas were: Diagnosis, Diagnostic imaging, Etiology, Severity assessment, Transfer indication, Fluid therapy, Nasogastric tube, Pain control, Antibiotics prophylaxis, Protease inhibitor, Nutritional support, Intensive care, Biliary Abdominal Compartment Syndrome, Interventions complications, Post-ERCP Clinical Indicator (Pancreatitis Bundles 2015). Meta-analysis following four randomized controlled trials: (1) prophylactic antibiotics use; (2) pancreatic stent placement prevention post-ERCP pancreatitis; (3) non-steroidal anti-inflammatory drugs (NSAIDs) (4) peritoneal lavage. Using create useful information. In addition, mobile application developed, made it possible diagnose, assess check bundles. Conclusions The using most up-to-date methods, including latest recommended medical treatments, we are confident that this will make them easy many clinicians use, provide tool decision-making process treatment patients, optimal support. free calculator is available via http://www.jshbps.jp/en/guideline/jpn-guideline2015.html