Management of gestational trophoblastic disease in developing countries.

摘要: In Malaysia, the incidence of molar pregnancy and gestational trophoblastic neoplasia is 2.8 1.59 per 1000 deliveries, respectively; disease more common among Chinese compared to Malays Indians. While uterine suction preferred method evacuation hydatidiform mole, complete was not achieved at first attempt in 25% cases. Partial moles comprise 30% all moles; these need follow up similar that for as they are potentially malignant. management invasive moles, chemotherapy should be withheld presence metastases or failure regression hCG. Placental site tumours rare. Prophylactic hysterectomy prophylactic recommended. However, those patients with unsatisfactory hCG curves indicating 'at risk' developing (GTN), 'selective preventive chemotherapy' appears appropriate. Chemotherapy remains main modality treatment GTN. As tumour bulk location important determinants outcome, we categorized our into low, medium- high-risk groups survivals 100, 98 61.7% respectively. Surgery radiotherapy have a limited role.