Research in Drug Allergy: A Search for Impurities?
作者： A. L. De Weck
DOI: 10.1007/978-3-642-49733-9_33
关键词: Reactivity (chemistry) 、 Drug 、 In vivo 、 Hapten 、 Sensitization 、 Drug allergy 、 Penicillin allergy 、 Pharmacology 、 Penicillin Acylase 、 Chemistry
摘要: Most drugs being low molecular weight chemicals eventually functioning as haptens, sensitization and allergic reactions to should (according the Landsteiner’s theory) only occur if drug or one of its reactive metabolites is able form suitable conjugates with autologous proteins in vivo. Accordingly, research on immunochemical mechanisms allergy has been mostly oriented towards study reactivity itself a search for derivatives, immunogenic conjugates.
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sci-hub.st 参考文章(13)
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