Cutaneous T-cell Lymphoma.

作者: L. Frank Glass , Karen L. Keller , Jane L. Messina , John Dalton , Cynthia Yag-Howard

DOI: 10.1177/107327489800500101

关键词: Treatment optionsMedicineImmunophenotypingDermatologyGene Rearrangement AnalysisEpidemiologyLymphomaHelper T lymphocyteCutaneous T-cell lymphomaDisease

摘要: BACKGROUND: Cutaneous T-cell lymphoma (CTCL) represents a spectrum of diseases composed malignant helper T lymphocytes. An accurate diagnosis early CTCL is difficult because the varied clinical and histologic expressions disease. METHODS: The authors review epidemiology, possible risk factors, manifestations, diagnostic techniques, staging, prognosis, treatment options for CTCL. RESULTS: often nonspecific presentations may delay thus necessitating further studies such as immunophenotyping, flow cytometry, receptor gene rearrangement analysis. CONCLUSIONS: A multidisciplinary approach to diagnosis, assists in optimizing outcomes from management patients with this

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