EZH2 is associated with poor prognosis in head-and-neck squamous cell carcinoma via regulating the epithelial-to-mesenchymal transition and chemosensitivity.
作者： Jae Won Chang , Seo Young Gwak , Geun-Ae Shim , Lihua Liu , Young Chang Lim
DOI: 10.1016/J.ORALONCOLOGY.2015.11.002
关键词: EZH2 、 Vimentin 、 Gene knockdown 、 Head and neck squamous-cell carcinoma 、 Biology 、 Epithelial–mesenchymal transition 、 Gene silencing 、 Cancer research 、 Cisplatin 、 Tissue microarray
摘要: … EZH2 is also associated with tumor aggressiveness via regulating the epithelial-to-mesenchymal transition. Furthermore, we show that high EZH2 … Our results indicate that EZH2 may …
sci-hub.se 参考文章(36)
Jiali Wang, Baoshan Liu, Hui Han, Qiuhuan Yuan, Mengyang Xue, Feng Xu, Yuguo Chen, Acute Hepatic Insulin Resistance Contributes to Hyperglycemia in Rats Following Myocardial Infarction Molecular Medicine. ,vol. 21, pp. 68- 76 ,(2015) , 10.2119/MOLMED.2014.00240
Wen Zhou, Jian Wang, Wang-Ying Man, Qing-Wei Zhang, Wen-Gui Xu, siRNA silencing EZH2 reverses cisplatin-resistance of human non-small cell lung and gastric cancer cells. Asian Pacific Journal of Cancer Prevention. ,vol. 16, pp. 2425- 2430 ,(2015) , 10.7314/APJCP.2015.16.6.2425
Ya-Jing Zhang, Qiao-Zhi Li, Chen Lin, Fei Huang, miR-101 suppresses tumor proliferation and migration, and induces apoptosis by targeting EZH2 in esophageal cancer cells. International Journal of Clinical and Experimental Pathology. ,vol. 7, pp. 6543- 6550 ,(2014)
Gang Wang, Yubei Sun, Yifu He, Chushu Ji, Bing Hu, Yuping Sun, miR-26a Promoted by Interferon-Alpha Inhibits Hepatocellular Carcinoma Proliferation and Migration by Blocking EZH2 Genetic Testing and Molecular Biomarkers. ,vol. 19, pp. 30- 36 ,(2015) , 10.1089/GTMB.2014.0245
Min Zheng, Ya-ping Jiang, Wei Chen, Kai-de Li, Xin Liu, Shi-yu Gao, Hao Feng, Sha-sha Wang, Jian Jiang, Xiang-rui Ma, Xiao Cen, Ya-jie Tang, Yu Chen, Yun-feng Lin, Ya-ling Tang, Xin-hua Liang, Snail and Slug collaborate on EMT and tumor metastasis through miR-101-mediated EZH2 axis in oral tongue squamous cell carcinoma. Oncotarget. ,vol. 6, pp. 6797- 6810 ,(2015) , 10.18632/ONCOTARGET.3180
HUALI WANG, YUNHAI YU, CHEN CHEN, QIAN WANG, TAISHENG HUANG, FANGZHEN HONG, LIN ZHU, Involvement of enhancer of zeste homolog 2 in cisplatin-resistance in ovarian cancer cells by interacting with several genes. Molecular Medicine Reports. ,vol. 12, pp. 2503- 2510 ,(2015) , 10.3892/MMR.2015.3745
Dong-liang Chen, Dong-sheng Zhang, Yun-xin Lu, Le-zong Chen, Zhao-lei Zeng, Ming-ming He, Feng-hua Wang, Yu-hong Li, Hui-zhong Zhang, Helene Pelicano, Wei Zhang, Rui-hua Xu, microRNA-217 inhibits tumor progression and metastasis by downregulating EZH2 and predicts favorable prognosis in gastric cancer Oncotarget. ,vol. 6, pp. 10868- 10879 ,(2015) , 10.18632/ONCOTARGET.3451
Luciana O. Almeida, Aline C. Abrahao, Luciana K. Rosselli-Murai, Fernanda S. Giudice, Chiara Zagni, Andreia M. Leopoldino, Cristiane H. Squarize, Rogerio M. Castilho, NFκB mediates cisplatin resistance through histone modifications in head and neck squamous cell carcinoma (HNSCC) FEBS Open Bio. ,vol. 4, pp. 96- 104 ,(2014) , 10.1016/J.FOB.2013.12.003
Jae Won Chang, Sung Un Kang, Yoo Seob Shin, Kang Il Kim, Seong Jin Seo, Sang Sik Yang, Jong-Soo Lee, Eunpyo Moon, Keunho Lee, Chul-Ho Kim, Non-Thermal Atmospheric Pressure Plasma Inhibits Thyroid Papillary Cancer Cell Invasion via Cytoskeletal Modulation, Altered MMP-2/-9/uPA Activity PLOS ONE. ,vol. 9, ,(2014) , 10.1371/JOURNAL.PONE.0092198
Q Cao, J Yu, S M Dhanasekaran, J H Kim, R-S Mani, S A Tomlins, R Mehra, B Laxman, X Cao, J Yu, C G Kleer, S Varambally, A M Chinnaiyan, Repression of E-cadherin by the polycomb group protein EZH2 in cancer Oncogene. ,vol. 27, pp. 7274- 7284 ,(2008) , 10.1038/ONC.2008.333