Epstein-Barr virus and HIV-AIDS-associated diseases
作者： K.L McClain
DOI: 10.1016/S0753-3322(01)00092-0
关键词: Herpesviridae 、 Virology 、 AIDS-related complex 、 Gammaherpesvirinae 、 Immunology 、 Epstein–Barr virus 、 Immune system 、 Virus 、 Viral transformation 、 Biology 、 Lymphatic system 、 Pharmacology 、 General Medicine
摘要: Among the secondary problems of patients with human immune deficiency virus (HIV) infection are lymphadenopathy, atypical lymphoproliferations, and malignant transformations lymphoid, muscle, epithelial cells caused by Epstein-Barr (EBV). The lymphoproliferative diseases associated EBV include lymphocytic interstitial pneumonitis, lymphomas primary extra-nodal sites, such as central nervous system (CNS), mucosa-associated lymphoid tissue (MALT). causes these through a combination mechanisms including use virus-encoded transforming genes, stimulation diverse cytokines, interaction receptors for tumor necrosis factor (TNF) family cytokines.
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