Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
作者： Naoko Takebe , Pamela J. Harris , Ronald Q. Warren , S. Percy Ivy
DOI: 10.1038/NRCLINONC.2010.196
关键词: Hedgehog 、 Cancer stem cell 、 Cancer cell 、 Cell biology 、 Stem cell 、 Biology 、 Progenitor cell 、 Wnt signaling pathway 、 Metastasis 、 Embryonic stem cell
摘要: Tumor relapse and metastasis remain major obstacles for improving overall cancer survival, which may be due at least in part to the existence of cancer stem cells (CSCs). CSCs are …
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