Prevalence and levels of antibodies to the circumsporozoite protein of Plasmodium falciparum in an endemic area and their relationship to resistance against malaria infection
作者： Fulvio Esposito , Stefania Lombardi , David Modiano , Fidel Zavala , Jan Reeme
DOI: 10.1016/0035-9203(88)90007-7
关键词: Antibody 、 Malaria 、 Inoculation 、 Endemic area 、 Vaccination 、 Plasmodium falciparum 、 Circumsporozoite protein 、 Transmission (medicine) 、 Virology 、 Biology 、 Public Health, Environmental and Occupational Health 、 Parasitology 、 Infectious Diseases 、 General Medicine
摘要: A study on malaria transmission, prevalence of infection and anti-sporozoite antibodies was carried out in Burkina Faso (West Africa). The the levels to (NANP)3 were found be related entomological sporozoite inoculation rates measured at same time a defined area. major inducer anti-(NANP)3 antibody production under field conditions is by infected mosquitoes. Levels vary considerably with age transmission season. High raised might offer protection against small inocula sporozoites.
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