Copeptin as a diagnostic biomarker for sepsis-related deaths.

作者: Cristian Palmiere , Marc Augsburger

DOI: 10.1016/J.PEPTIDES.2014.07.011

关键词: Septic shockAutopsyDiagnostic biomarkerSepsisGastroenterologyCopeptinIn patientIntensive care medicineInternal medicineInterleukin 6MedicineProcalcitonin

摘要: Copeptin has been shown to increase in patients with sepsis, severe sepsis and septic shock. In the study herein described, copeptin was measured a series of sepsis-related fatalities control cases that underwent medico-legal investigations. No age-dependent differences levels either or were observed. correlation between concentrations postmortem interval identified group. significantly higher cases. Moreover, correlated procalcitonin, C-reactive protein interleukin 6 values. These preliminary findings seem indicate can be reliably biological samples collected during results also suggest hemodynamic instability associated shock characterized by measurement forensic casework.

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