Intrahepatic cholestasis related to vanishing bile duct syndrome in Hodgkin's disease.

作者: F Gottrand , F Cullu , F Mazingue , B Nelken , M Lecomte-Houcke

DOI: 10.1097/00005176-199704000-00013

关键词: Internal medicineMedicineBiliary tract diseaseCholestasisPathologyDiseaseVanishing bile duct syndromeLymphomaHodgkin sBiliary tractGastroenterologyJaundice

摘要: DISCUSSION When jaundice is present in HD, a satisfactory explanation for the hyperbilirubinemia cannot be found in every case even at autopsy (1-3). Perrera et al.(1) reviewed seven cases of unexplained hyperbilirubinemia in HD; five patients died 5-19 months after the onset of jaundice and the two remaining patients who responded to radiotherapy improved. Recently, Hubscher et al.(5), in addition to cholestasis of unknown etiology, found VBDS on subsequent review of the histological material of three patients. We …

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