作者: Marta Soares Rossini , Irene Lorand-Metze , Gislaine Borba Oliveira , Cármino Antonio De Souza
DOI: 10.1590/S1516-31802000000500008
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摘要: CONTEXT: Liver damage is relatively common in patients affected by Hodgkin's disease. A smaller proportion of cases develops jaundice. Recently, the vanishing bile duct syndrome was described The mechanisms this severe complication have been poorly understood until now. OBJECTIVE: To describe a rare case intra-hepatic cholestasis due to syndrome. DESIGN: Case report. CASE REPORT: 38-year-old male patient biopsy showed no detectable Intra-hepatic found and none six portal tracts analyzed contained normal ducts. treatment based on conventional high-dose escalation chemotherapy. died from an irreversible liver failure while complete remission