Effects of Multiple Virus Coinfections on Disease Progression in HIV-Positive Patients

摘要: Objective: Since virus infections in AIDS patients are mostly inevitable and as they frequently cause disease deterioration therapeutic failures, a comprehensive investigation was made of the influence coinfections 9 well-known viruses on progression infected with human immunodeficiency type 1 (HIV). Methods: A cross-sectional study 62 HIV-positive conducted to correlate prevalence rates for alanine aminotransferase (ALT) levels CD4 cell counts patients. Results: The significantly higher than those control groups. Furthermore, almost one third studied group coinfected transfusion-transmitted (TTV) manifested ALT (p = 0.020), these were raised further if coinfection TTV hepatitis C had occurred 0.010). By analyzing counts, only significant effect which could be detected herpesvirus 8. Conclusion: This result confirmed that immune-suppressed persons more vulnerable common infections. Unlike B or virus, seems accelerate chronic HIV-infected