TT virus infection in human immunodeficiency virus type 1 infected mothers and their infants.

摘要: Serum TT virus (TTV) DNA was determined in 83 human immunodeficiency type 1 (HIV 1) infected mothers [46 intravenous drug user and 37 non-intravenous women] their infants. Twenty-nine (34.9%) were TTV infected. Infection more frequent among than [21/46 (45.6%) vs. 8/37 (21.6%); relative risk (RR): 2.1; 95% confidence limits (95% CL): 1.1-4.2; P= 0.023] users who carried on injecting those had given it up [10/14 (71.4%) 11/ 32 (34.3%); RR: 2.1 (95%CL: 1.2-3.7); P = 0.021]. not related to age, CD4-positive T-lymphocyte counts, HIV load, hepatitis B (HBV), G/GB-C (GBV-C/HGV), C (HCV) exposure. Eight (27.5%) infants born (but none of uninfected) at a median age 1.5 (range: 0.6-2.8) months. Infants by vaginal/emergency caesarean delivery frequently elective [7/16 (43.7%) 1/13 (7.6%); 95%CL: 1.2-3.5; 0.033]. maternal 1, HBV, GBV-C/HGV, or HCV transmission. No infant became thereafter. child [follow-up: 31 (median; range: 6-60) months] showed signs liver disease; five cleared after 22 infection women is prevalently user. The findings suggest that may acquire birth. persist without evident disease.