Clinicopathologic Correlation of Ocular Surface Squamous Neoplasms at Bascom Palmer Eye Institute: 2001 to 2010

摘要: Purpose To describe the clinical and histologic characteristics of ocular surface squamous neoplasia (OSSN) lesions provide clinicopathologic correlation to determine features that may indicate higher-grade lesions. Design Retrospective case series. Participants A total 612 consecutive OSSN sent Bascom Palmer pathology laboratory from January 1, 2001 September 20, 2010. Methods Pathologic examination by a single experienced pathologist (S.R.D.). Review records patient charts. Main Outcome Measures Correlation factors histology OSSN. Results Over studied period, 33% submitted specimens were characterized as mild, moderate, or severe dysplasia; 52% classified carcinoma in situ; 11% graded cell carcinoma. Characteristics associated with included male gender, biopsy at Eye Institute, temporal superior locations, lack corneal involvement, papillomatous nodular appearance, microscopic multifocality, positive margins on biopsy. Conclusions Certain are These findings help clinicians more accurately evaluate anticipate pathologic grade conjunctival suspected be Financial Disclosure(s) The author(s) have no proprietary commercial interest any materials discussed this article.