Hyperthermia and disaggregation of brain polysomes induced by bacterial pyrogen

作者: John J. Heikkila , Ian R. Brown

DOI: 10.1016/0024-3205(79)90266-2

关键词: PolysomeBiochemistryHyperthermia inducedBacterial PyrogenMessenger RNAHyperthermiaKidneyRibonucleaseCell biologyChemistry

摘要: Abstract Hyperthermia induced following injection of bacterial pyrogen to rabbits was associated with a disaggregation brain polysomes monosomes. Direct elevation the body temperature levels similar that found after administration also resulted in polysome shift. The either or ambient not due ribonuclease activation and phenomenon relocalization polyadenylated mRNA from Since kidney, it appears may be more sensitive elevations temperature.

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