The origin of plasma alkaline phosphatase activity in mice and rats
作者： Lawrence A. Menahan , Kathleen A. Sobocinski , B. Peter Austin
DOI: 10.1016/0305-0491(84)90026-9
关键词: Phenylalanine 、 Urea denaturation 、 Biology 、 Enzyme 、 Metabolism 、 Isozyme 、 Enzyme assay 、 Internal medicine 、 Alkaline phosphatase 、 Endocrinology 、 Ratón
摘要: Abstract 1. Swiss albino mice displayed the highest activity of alkaline phosphatase at 4–6 weeks with a precipitous decline by 18 age to value seen in mature animal. 2. Circulating was significantly higher rat than mouse fed state. With fasting, enzyme declined yet increased mouse. The net result plasma after 48 hr fast. 3. l -Phenylalanine inhibition greater from 4. Yet condition, -homoarginine and -p-bromotetramisole inhibited extent rats. 5. Heat inactivation as well urea denaturation faster 6. Thus, it appears that isoenzyme skeletal origin contributes proportion circulating occurs Sprague-Dawley which intestinal plays role condition.
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