Detection and separation of aminoglycosides by binding to immobilized lysozyme or α-lactalbumin

摘要: Aminoglycosides such as aminoglycoside antibiotics are detected and separated by non-immunoaffinity binding to an immobilized protein which is preferably lysozyme or α-lactalbumin. in a biological sample milk fermentation broth contacting the with on solid carrier particles of carboxylated latex bind aminoglycosides protein, adding label that binds measuring label. In another embodiment, containing bound from sample, removed added measured. passing through bioreactor recovering free aminoglycosides. The may be eluted protein.