作者: Ana P Tedim , Patricia Ruiz-Garbajosa , Jukka Corander , Concepción M Rodríguez , Rafael Cantón
DOI: 10.1128/AEM.03661-14
关键词: Population 、 Genotype 、 Enterococcus faecium 、 Feces 、 Microbiology 、 Antibiotic resistance 、 Colonization 、 Enterococcus 、 Biology 、 Enterococcus faecalis
摘要: The diversity of enterococcal populations from fecal samples hospitalized (n = 133) and nonhospitalized individuals 173) different age groups (group I, ages 0 to 19 years; group II, 20 59 III, ≥60 years) was analyzed. Enterococci were recovered at similar rates persons (77.44% 79.77%) all (75.0% 82.61%). Enterococcus faecalis faecium predominant, although seven other species identified. E. (including ampicillin-resistant faecium) colonization in independent. For inpatients, independent, but (particularly the colonization) significantly increased with age. population structure determined by superimposing goeBURST Bayesian analysis (BAPS). Most sequence types (STs; 150 isolates belonging 75 STs) linked BAPS 1 (22.0%), 2 (31.3%), 3 (36.7%). A positive association between hospital subgroups 2.1a 3.3a (which included major human lineages) community-based 1.2 3.3b found. (130 58 grouped into groups, (36.9%), (40.0%), (23.1%), each one comprising widespread lineages. No associations or hospitalization established. dynamics microbiota healthy humans are largely unexplored, available knowledge being fragmented contradictory. study offers a novel comprehensive landscapes suggests that patients differ, predominance certain clonal lineages, often elderly individuals, occurring setting.