Preparation of surface-imprinted microspheres effectively controlled by orientated template immobilization using highly cross-linked raspberry-like microspheres for the selective recognition of an immunostimulating peptide

摘要: Surface-imprinted microspheres were controllably synthesized using ionic liquid-functionalized with a highly cross-linked raspberry-like structure as the matrix via surface molecular self-assembly and precipitation polymerization in aqueous media at room temperature. An immunostimulating hexapeptide from human (IHH) medical properties was chosen template molecule preparation of different molecularly imprinted (MIMs). The experiment process tracked as-prepared well characterized. Results reveal that adsorption capacity selective recognition MIMs have direct relationship functional chain microspheres. Moreover, both high good used competitive rebinding tests analysis urine samples, which demonstrated their potential use for IHH enrichment real samples.