The prevalence of intrinsic subtypes and prognosis in breast cancer patients of different races.
作者： Junichi Kurebayashi , Takuya Moriya , Takanori Ishida , Hisashi Hirakawa , Masafumi Kurosumi
DOI: 10.1016/J.BREAST.2007.07.017
关键词: Breast cancer 、 Internal medicine 、 Survival analysis 、 Cohort study 、 Survival rate 、 Cytokeratin 、 In patient 、 Progesterone receptor 、 Estrogen receptor 、 Oncology 、 Medicine
摘要: A recent report indicated that a high prevalence of basal-like breast tumors (estrogen receptor [ER]-negative, progesterone [PR]-negative, human epidermal growth factor [HER] 2-negative, and cytokeratin 5/6-positive and/or HER1-positive) could contribute to poor prognosis in African American women with cancer. It has been reported Japanese cancer have significantly better survival rate than other races the USA. These findings suggest cancers favorable biological characteristics. To clarify this hypothesis, we conducted cohort study investigate intrinsic subtypes for each subtype 793 patients. This revealed very low (only 8%) aggressive characteristics Survival analysis showed poorer patients those luminal (ER- PR-positive, HER2-negative) support hypothesis more races. In conclusion, influence different The should be taken into account when analyzing data multi-racial/international clinical study.
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sci-hub.se 参考文章(30)
Anthony P. Polednak, Racial Differences in Mortality from Obesity-Related Chronic Diseases in US Women Diagnosed with Breast Cancer Ethnicity & Disease. ,vol. 14, pp. 463- ,(2004) , 10.13016/OS5I-G5NH
Peggy L. Porter, Mary Jo Lund, Ming Gang Lin, Xiaopu Yuan, Jonathan M. Liff, Elaine W. Flagg, Ralph J. Coates, J. William Eley, Racial differences in the expression of cell cycle-regulatory proteins in breast carcinoma Cancer. ,vol. 100, pp. 2533- 2542 ,(2004) , 10.1002/CNCR.20279
Paul Peter Rosen, Rosen's Breast Pathology ,(1997)
Xiaowei Zhang, Kimberly M. Rieger-Christ, Ian C. Summerhayes, David E. Wazer, K. Eric Paulson, Amy S. Yee, Jiyoung Kim, Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1. Journal of Biological Chemistry. ,vol. 281, pp. 10865- 10875 ,(2006) , 10.1074/JBC.M513378200
Sue A. Joslyn, Racial differences in treatment and survival from early-stage breast carcinoma. Cancer. ,vol. 95, pp. 1759- 1766 ,(2002) , 10.1002/CNCR.10827
Franco Sassi, Harold S. Luft, Edward Guadagnoli, Reducing Racial/Ethnic Disparities in Female Breast Cancer: Screening Rates and Stage at Diagnosis American Journal of Public Health. ,vol. 96, pp. 2165- 2172 ,(2006) , 10.2105/AJPH.2005.071761
Emad A. Rakha, Maysa E. El-Sayed, Andrew R. Green, Andrew H. S. Lee, John F. Robertson, Ian O. Ellis, Prognostic markers in triple-negative breast cancer Cancer. ,vol. 109, pp. 25- 32 ,(2007) , 10.1002/CNCR.22381
R L H Bigelow, J A Cardelli, The green tea catechins, (−)-Epigallocatechin-3-gallate (EGCG) and (−)-Epicatechin-3-gallate (ECG), inhibit HGF/Met signaling in immortalized and tumorigenic breast epithelial cells Oncogene. ,vol. 25, pp. 1922- 1930 ,(2006) , 10.1038/SJ.ONC.1209227
Christopher I. Li, Kathleen E. Malone, Janet R. Daling, Differences in Breast Cancer Stage, Treatment, and Survival by Race and Ethnicity Archives of Internal Medicine. ,vol. 163, pp. 49- 56 ,(2003) , 10.1001/ARCHINTE.163.1.49
Rebecca Smith-Bindman, Diana L. Miglioretti, Nicole Lurie, Linn Abraham, Rachel Ballard Barbash, Jodi Strzelczyk, Mark Dignan, William E. Barlow, Cherry M. Beasley, Karla Kerlikowske, Does utilization of screening mammography explain racial and ethnic differences in breast cancer Annals of Internal Medicine. ,vol. 144, pp. 541- 553 ,(2006) , 10.7326/0003-4819-144-8-200604180-00004