Statin-Based Palliative Therapy for Hepatocellular Carcinoma.
作者： Joni Yu-Hsuan Shao , Fei-Peng Lee , Chia-Lun Chang , Szu-Yuan Wu
DOI: 10.1097/MD.0000000000001801
关键词: Percutaneous ethanol injection 、 Palliative care 、 Oncology 、 Liver transplantation 、 Hepatocellular carcinoma 、 Cancer 、 Cancer registry 、 Internal medicine 、 Hepatitis B virus 、 Surgery 、 Medicine 、 Hepatitis B
摘要: Most hepatocellular carcinoma (HCC) patients worldwide do not receive curative treatments. Alternative treatments for most HCC include palliative treatments, such as transarterial chemoembolization (TACE), chemotherapy, and radiotherapy. Although statins may be a chemopreventive treatment option reducing hepatitis B virus (HBV)- C (HCV)-related risks, their therapeutic effects are unknown. This study evaluated the of statin on receiving treatment.Data from National Health Insurance claims database cancer registry databases The Collaboration Center Information Application, Taiwan, were analyzed. We included who treated between January 1, 2001, December 31, 2010, followed them index date to 2012. inclusion criteria presence HBV carrier-related HCC, age >20 years, having received TACE, radiotherapy, or chemotherapy treatment. exclusion diagnosis before was confirmed, surgery, liver transplantation, radiofrequency ablation, percutaneous ethanol injection treatment, missing sex-related information, HBV, 50% reduction in deaths).
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