The cytochemical bioassay of hormones.
作者： J. CHAYEN , J.R. DALY , N. LOVERIDGE , LUCILLE BITENSKY
DOI: 10.1016/B978-0-12-571132-6.50009-9
关键词: Biologically active substances 、 Cytochemistry 、 Biological activity 、 Bioassay 、 Hormone 、 Biochemistry 、 Cytochemical bioassay 、 Biology 、 Immunology 、 Orders of magnitude (mass) 、 Radioimmunoassay
摘要: Publisher Summary The evidence summarized in this chapter shows that it is possible to precisely measure the biochemical changes induced target cells when specific hormone acts on these with modern techniques of cellular biology and cytochemistry. By measuring such effects, assay biological activity a degree sensitivity exceeds most currently available radioimmunoassays by two three orders magnitude. increase use cytochemical bioassays have resulted their validity tests applicability scope. development section for adrenocoticotropin (ACTH) has extension assays routine purposes. It model similar other hormones. But principle effect bioreactive molecules tissues can be measured very sensitively opens further vistas. These applied detection, assay, biologically active substances, as pharmacologically substances or toxic substances. readily used study analysis end-organ effects hormones products body studied new techniques.
sci-hub.st 参考文章(78)
S. ROSALYN YALOW, Heterogeneity of Peptide Hormones Recent Progress in Hormone Research. ,vol. 30, pp. 597- 633 ,(1974) , 10.1016/B978-0-12-571130-2.50020-1
E DEELEY, H DAVIES, J CHAYEN, The DNA content of cells in the root of Experimental Cell Research. ,vol. 12, pp. 582- 591 ,(1957) , 10.1016/0014-4827(57)90174-X
J. CHAYEN, LUCILLE BITENSKY, R.G. BUTCHER, F.P. ALTMAN, Cellular biochemical assessment of steroid activity. Advances in steroid biochemistry and pharmacology. ,vol. 4, pp. 1- 60 ,(1974) , 10.1016/B978-0-12-037504-2.50004-3
R. G. Butcher, The chemical determination of section thickness. Histochemistry and Cell Biology. ,vol. 28, pp. 131- 136 ,(1971) , 10.1007/BF00279857
Elizabeth K. Patterson, Shu-Hsi Hsiao, Augusta Keppel, STUDIES ON DIPEPTIDASES AND AMINOPEPTIDASES. I. DISTINCTION BETWEEN LEUCINE AMINOPEPTIDASE AND ENZYMES THAT HYDROLYZE L-LEUCYL-BETA-NAPHTHYLAMIDE. Journal of Biological Chemistry. ,vol. 238, pp. 3611- 3620 ,(1963) , 10.1016/S0021-9258(19)75316-2
Elizabeth K. Patterson, Shu-Hsi Hsiao, Augusta Keppel, Sam Sorof, STUDIES ON DIPEPTIDASES AND AMINOPEPTIDASES. II. ZONAL ELECTROPHORETIC SEPARATION OF RAT LIVER PEPTIDASES. Journal of Biological Chemistry. ,vol. 240, pp. 710- 716 ,(1963) , 10.1016/S0021-9258(17)45233-1
R.G. Butcher, Studies on succinate oxidation: I. The use of intact tissue sections Experimental Cell Research. ,vol. 60, pp. 54- 60 ,(1970) , 10.1016/0014-4827(70)90488-X
D.C. Morley, Cold injury among children severely ill in the tropics. The Lancet. ,vol. 2, pp. 1170- 1171 ,(1960) , 10.1016/S0140-6736(60)92358-8
N Marks, R K Datta, A Lajtha, Partial Resolution of Brain Arylamidases and Aminopeptidases Journal of Biological Chemistry. ,vol. 243, pp. 2882- 2889 ,(1968) , 10.1016/S0021-9258(18)93354-5
J.E. Dumont, The action of thyrotropin on thyroid metabolism. Vitamins and Hormones Series. ,vol. 29, pp. 287- 412 ,(1971) , 10.1016/S0083-6729(08)60051-5