Diagnosis of metastatic neoplasms: an immunohistochemical approach.

摘要: Abstract Context.—It is important to determine the type and/or site of origin metastatic tumors for optimal clinical management. Objective.—To summarize use currently available immunohistochemical markers in evaluation tumors. Data Sources.—Review relevant literature on and author's personal experience. Conclusions.—Immunohistochemistry an ancillary technique should be used context routine morphology information. While a single marker may support known or suspected origin, carefully constructed panel strongly recommended, particularly morphologically uncertain lineage origin.