Sewage effluent from an Indian hospital harbors novel carbapenemases and integron-borne antibiotic resistance genes.

作者: Nachiket P. Marathe , Fanny Berglund , Mohammad Razavi , Chandan Pal , Johannes Dröge

DOI: 10.1186/S40168-019-0710-X

关键词: Escherichia coliBiology16S ribosomal RNAAntibiotic resistanceDNA sequencingMobile genetic elementsGeneticsIntegronGeneResistome

摘要: … the ability to identify novel ARGs without apparent similarities to known ARGs as it is based … host like Escherichia coli [12]. With such an approach, we have identified novel ARGs, …

参考文章(75)
Molly K Gibson, Kevin J Forsberg, Gautam Dantas, Improved annotation of antibiotic resistance determinants reveals microbial resistomes cluster by ecology The ISME Journal. ,vol. 9, pp. 207- 216 ,(2015) , 10.1038/ISMEJ.2014.106
Dongeun Yong, Mark A. Toleman, Jan Bell, Brett Ritchie, Rachael Pratt, Henry Ryley, Timothy R. Walsh, Genetic and Biochemical Characterization of an Acquired Subgroup B3 Metallo-β-Lactamase Gene,blaAIM-1, and Its Unique Genetic Context in Pseudomonas aeruginosa from Australia Antimicrobial Agents and Chemotherapy. ,vol. 56, pp. 6154- 6159 ,(2012) , 10.1128/AAC.05654-11
Kevin Horan, Christian R Shelton, Thomas Girke, Predicting conserved protein motifs with Sub-HMMs. BMC Bioinformatics. ,vol. 11, pp. 205- 205 ,(2010) , 10.1186/1471-2105-11-205
Michael R. Gillings, Integrons: Past, Present, and Future Microbiology and Molecular Biology Reviews. ,vol. 78, pp. 257- 277 ,(2014) , 10.1128/MMBR.00056-13
Fredrik Boulund, Anna Johnning, Mariana Buongermino Pereira, DG Joakim Larsson, Erik Kristiansson, A novel method to discover fluoroquinolone antibiotic resistance (qnr) genes in fragmented nucleotide sequences. BMC Genomics. ,vol. 13, pp. 695- 695 ,(2012) , 10.1186/1471-2164-13-695
Kevin J. Forsberg, Sanket Patel, Molly K. Gibson, Christian L. Lauber, Rob Knight, Noah Fierer, Gautam Dantas, Bacterial phylogeny structures soil resistomes across habitats Nature. ,vol. 509, pp. 612- 616 ,(2014) , 10.1038/NATURE13377
Barry G. Hall, Stephen J. Salipante, Miriam Barlow, The Metallo-β-Lactamases Fall into Two Distinct Phylogenetic Groups Journal of Molecular Evolution. ,vol. 57, pp. 249- 254 ,(2003) , 10.1007/S00239-003-2471-0
M Watanabe, S Iyobe, M Inoue, S Mitsuhashi, Transferable imipenem resistance in Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy. ,vol. 35, pp. 147- 151 ,(1991) , 10.1128/AAC.35.1.147
Niklas Palmqvist, Elisabet Josefsson, Andrzej Tarkowski, Clumping factor A-mediated virulence during Staphylococcus aureus infection is retained despite fibrinogen depletion. Microbes and Infection. ,vol. 6, pp. 196- 201 ,(2004) , 10.1016/J.MICINF.2003.10.014