Molecular mechanisms linking the evolutionary conserved TORC1-Sch9 nutrient signalling branch to lifespan regulation inSaccharomyces cerevisiae
作者： Erwin Swinnen , Ruben Ghillebert , Tobias Wilms , Joris Winderickx
关键词: Signal transduction 、 Saccharomyces cerevisiae 、 Calorie restriction 、 Transcription factor 、 Yeast 、 Effector 、 Protein phosphatase 2 、 Cell biology 、 Genetics 、 Biology 、 Kinase 、 Applied Microbiology and Biotechnology 、 Microbiology 、 General Medicine
摘要: … TORC1 stimulates growth and inhibits stress responses largely by activating Sch9 and inhibiting Tap42, a regulatory subunit … binding to the Kog1 subunit of the TORC1 complex, thereby …
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