Autoantibodies in liver disease: important clues for the diagnosis, disease activity and prognosis.

作者: Takashi Himoto , Mikio Nishioka

DOI: 10.1007/S13317-013-0046-7

关键词: Anti-SSA/Ro autoantibodiesHepatitisPrimary biliary cirrhosisAnti-thyroid autoantibodiesLiver diseaseAutoimmune hepatitisAlcoholic liver diseaseImmunologyMedicinePrimary sclerosing cholangitis

摘要: It has been well established that numerous kinds of autoantibodies have detected in liver disease. Some may be helpful the diagnosis autoimmune diseases including hepatitis, primary biliary cirrhosis or sclerosing cholangitis. However, these are present even sera patients with viral drug-induced alcoholic disease, non-alcoholic fatty disease and hepatocelluar carcinoma as diseases. Other recognized predictive hallmarks for activity prognosis On other hand, treatment interferon initiates production several types chronic hepatitis C virus infection. induced by postulate outcome those patients. Recent studies also revealed close correlation between oxidative stress This article primarily reviews recent advances discusses clinical significance autoantibodies.

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