Second primary cancer risk of radiation therapy after radical prostatectomy for prostate cancer: an analysis of SEER data.
作者： May Abdel-Wahab , Isildinha M. Reis , Jiuhua Wu , Robert Duncan
DOI: 10.1016/J.UROLOGY.2009.02.085
关键词: Prostatectomy 、 Cancer 、 Absolute risk reduction 、 Prostate cancer 、 Radical surgery 、 Radiation therapy 、 Urology 、 Medicine 、 Risk factor 、 Surgery 、 Rectum
摘要: Objectives To determine the incidence of second primary cancer (SPC) and pelvic late SPC/radiation-induced SPC after radical prostatectomy radiation. Methods A total 228 235 prostate patients in 1973-2002 Surveillance, Epidemiology, End Results database were studied. The age-adjusted estimates SPCs was calculated. Competing risk multivariable Cox proportional hazards regression analysis adjusted for age at diagnosis, race or ethnicity, radiation used to evaluate effect treatment on SPC. overall 8.4%. most frequent bladder (2303 cases), rectum rectosigmoid junction (1006 cases). nonpelvic bronchus lung (4131 colon (2665 skin (1769 absolute developing a malignancy 1747 cases per 100 000 "Radical surgery x-ray treatment" group 1581 "radical surgery" group. With regard SPC, higher rate 374 seen radiated Conclusions Radiation increased No increases secondary extrapelvic SPCs.
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sci-hub.se 参考文章(22)
S Warren, Multiple primary malignant tumors. A survey of the literature and a statistical study American Journal of Cancer. ,vol. 16, pp. 1358- 1414 ,(1932)
William G. Cahan, Helen Q. Woodard, Norman L. Higinbotham, Fred W. Stewart, Bradley L. Coley, Sarcoma arising in irradiated bone Cancer. ,vol. 82, pp. 8- 34 ,(1998) , 10.1002/(SICI)1097-0142(19980101)82:1<8::AID-CNCR3>3.0.CO;2-W
William G. Cahan, Helen Q. Woodard, Norman L. Higinbotham, Fred W. Stewart, Bradley L. Coley, Sarcoma in irradiated bone. Report of eleven cases Cancer. ,vol. 1, pp. 3- 29 ,(1948) , 10.1002/1097-0142(194805)1:1<3::AID-CNCR2820010103>3.0.CO;2-7
Tom Pickles, Norm Phillips, The risk of second malignancy in men with prostate cancer treated with or without radiation in British Columbia, 1984–2000 Radiotherapy and Oncology. ,vol. 65, pp. 145- 151 ,(2002) , 10.1016/S0167-8140(02)00307-9
Benjamin Movsas, Alexandra L Hanlon, Wayne Pinover, Gerald E Hanks, Is there an increased risk of second primaries following prostate irradiation International Journal of Radiation Oncology Biology Physics. ,vol. 41, pp. 251- 255 ,(1996) , 10.1016/S0360-3016(97)00570-1
Alfred I. Neugut, Habibul Ahsan, Eliezer Robinson, Ronald D. Ennis, Bladder carcinoma and other second malignancies after radiotherapy for prostate carcinoma Cancer. ,vol. 79, pp. 1600- 1604 ,(1997) , 10.1002/(SICI)1097-0142(19970415)79:8<1600::AID-CNCR24>3.0.CO;2-0
Jason P. Fine, Robert J. Gray, A Proportional Hazards Model for the Subdistribution of a Competing Risk Journal of the American Statistical Association. ,vol. 94, pp. 496- 509 ,(1999) , 10.1080/01621459.1999.10474144
Ian M. Thompson, Catherine M. Tangen, Jorge Paradelo, M. Scott Lucia, Gary Miller, Dean Troyer, Edward Messing, Jeffrey Forman, Joseph Chin, Gregory Swanson, Edith Canby-Hagino, E. David Crawford, Adjuvant radiotherapy for pathologically advanced prostate cancer: a randomized clinical trial. JAMA. ,vol. 296, pp. 2329- 2335 ,(2006) , 10.1001/JAMA.296.19.2329
May Abdel-Wahab, Isildinha M. Reis, Kara Hamilton, Second Primary Cancer After Radiotherapy for Prostate Cancer—A SEER Analysis of Brachytherapy Versus External Beam Radiotherapy International Journal of Radiation Oncology*Biology*Physics. ,vol. 72, pp. 58- 68 ,(2008) , 10.1016/J.IJROBP.2007.12.043
Wayne S. Kendal, Libni Eapen, Robert MacRae, Shawn Malone, Garth Nicholas, Prostatic irradiation is not associated with any measurable increase in the risk of subsequent rectal cancer International Journal of Radiation Oncology Biology Physics. ,vol. 65, pp. 661- 668 ,(2006) , 10.1016/J.IJROBP.2005.11.013