Principles of Genetics and Genomics

作者: Sharon A. Savage

DOI: 10.1016/B978-0-12-384978-6.00010-8

关键词: Computational and Statistical GeneticsBiologyGenomicsComputational biologyInheritance (genetic algorithm)GeneticsHuman genomeGenetic variants

摘要: The last decade has brought remarkable advances in our understanding of the human genome, inheritance, and genetic contribution to disease. field grown from studies rare, highly-penetrant mutations associations between common variants diseases. analyses data generated these have led creation an entirely new scientific discipline, bioinformatics, which combines biology genetics with advanced computational methods.

参考文章(43)
Caroline May, Frederic Brosseron, Piotr Chartowski, Cornelia Schumbrutzki, Bodo Schoenebeck, Katrin Marcus, Instruments and methods in proteomics. Methods of Molecular Biology. ,vol. 696, pp. 3- 26 ,(2011) , 10.1007/978-1-60761-987-1_1
Maria Teresa Landi, Nilanjan Chatterjee, Kai Yu, Lynn R. Goldin, Alisa M. Goldstein, Melissa Rotunno, Lisa Mirabello, Kevin Jacobs, William Wheeler, Meredith Yeager, Andrew W. Bergen, Qizhai Li, Dario Consonni, Angela C. Pesatori, Sholom Wacholder, Michael Thun, Ryan Diver, Martin Oken, Jarmo Virtamo, Demetrius Albanes, Zhaoming Wang, Laurie Burdette, Kimberly F. Doheny, Elizabeth W. Pugh, Cathy Laurie, Paul Brennan, Rayjean Hung, Valerie Gaborieau, James D. McKay, Mark Lathrop, John McLaughlin, Ying Wang, Ming-Sound Tsao, Margaret R. Spitz, Yufei Wang, Hans Krokan, Lars Vatten, Frank Skorpen, Egil Arnesen, Simone Benhamou, Christine Bouchard, Andres Metsapalu, Tonu Vooder, Mari Nelis, Kristian Välk, John K. Field, Chu Chen, Gary Goodman, Patrick Sulem, Gudmar Thorleifsson, Thorunn Rafnar, Timothy Eisen, Wiebke Sauter, Albert Rosenberger, Heike Bickeböller, Angela Risch, Jenny Chang-Claude, H. Erich Wichmann, Kari Stefansson, Richard Houlston, Christopher I. Amos, Joseph F. Fraumeni, Sharon A. Savage, Pier Alberto Bertazzi, Margaret A. Tucker, Stephen Chanock, Neil E. Caporaso, A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma. American Journal of Human Genetics. ,vol. 85, pp. 679- 691 ,(2009) , 10.1016/J.AJHG.2009.09.012
Wei Yu, Marta Gwinn, Melinda Clyne, Ajay Yesupriya, Muin J Khoury, A navigator for human genome epidemiology Nature Genetics. ,vol. 40, pp. 124- 125 ,(2008) , 10.1038/NG0208-124
Eric S Lander, None, Initial impact of the sequencing of the human genome Nature. ,vol. 470, pp. 187- 197 ,(2011) , 10.1038/NATURE09792
Yonqing Zhang, Supriyo De, John R Garner, Kirstin Smith, S Alex Wang, Kevin G Becker, Systematic analysis, comparison, and integration of disease based human genetic association data and mouse genetic phenotypic information BMC Medical Genomics. ,vol. 3, pp. 1- 22 ,(2010) , 10.1186/1755-8794-3-1
Alistair R.R. Forrest, Piero Carninci, Whole genome transcriptome analysis RNA Biology. ,vol. 6, pp. 107- 112 ,(2009) , 10.4161/RNA.6.2.7931
, Completing the map of human genetic variation. Nature. ,vol. 447, pp. 161- 165 ,(2007) , 10.1038/447161A
Eric D. Green, , Mark S. Guyer, Charting a course for genomic medicine from base pairs to bedside Nature. ,vol. 470, pp. 204- 213 ,(2011) , 10.1038/NATURE09764
David J. Hunter, Muin J. Khoury, Jeffrey M. Drazen, Letting the genome out of the bottle--will we get our wish? The New England Journal of Medicine. ,vol. 358, pp. 105- 107 ,(2008) , 10.1056/NEJMP0708162
Duncan M. Baird, Variation at the TERT locus and predisposition for cancer Expert Reviews in Molecular Medicine. ,vol. 12, ,(2010) , 10.1017/S146239941000147X