Interactions between herbs and antidiabetics: an overview of the mechanisms, evidence, importance, and management.

摘要: Complementary and alternative therapies are quickly gaining importance because they perceived to be free of side effects due their natural origin. However, herbal remedies complex mixtures bioactive entities, which may interact with prescription drugs through pharmacokinetic or pharmacodynamic mechanisms sometimes result in life-threatening consequences. In particular, diabetes patients often treated multiple medications different comorbidities, such use antidiabetic for entire lives; thus, it is important make the public aware herb interactions drugs. this paper, we summarize reports available on interaction oral hypoglycemic agents describe mechanisms, preclinical clinical evidence, importance, management strategies.