Association between Serum Cholesterol Level and Osteoporotic Fractures.

摘要: Objective: Previous epidemiological studies have found an association between serum cholesterol level and bone mineral density. However, evaluating the incidence of osteoporotic fracture are scant. Therefore, objective this study was to investigate whether levels in Chinese participants aged 55 years or older associated with increased risk fracture. Materials Methods: We performed a cross-sectional study, including 1791 (62.1% postmenopausal women 213 fractures). Standardized self-administered questionnaires, physical examination, laboratory tests, dual-energy X-ray absorptiometry examination were performed. Multivariate-adjusted logistic regression models used evaluate associations (total (TC), triglycerides (TG), high-density lipoprotein (HDL-C), low-density (LDL-C)) risk. Results: After adjusting for potential confounding factors, there no per standard deviation (SD) increase TC LDL total participants, men as individual groups. There significant SD HDL-C (odds ratio [OR] 1.20, 95% confidence interval [CI] 1.03, 1.40, P = 0.023) (OR 1.37, CI 1.12, 1.68, 0.003), whereas observed 1.01, 0.73, 0.951). Additionally, we TG 1.04, 1.38, 0.015). In women, nonlinear relationship The above 1.64 mmol/L 1.93, 1.24, 3.00, 0.0038). Conclusions: Among adults, is significantly fractures overall mmol/L.