Overexpression of AIB1 correlates inversely with E-cadherin expression in pancreatic adenocarcinoma and may promote lymph node metastasis
作者： Si Guo , JingJing Xu , Rui Xue , YuQiong Liu , HaiBo Yu
DOI: 10.1007/S10147-013-0549-2
关键词: Medicine 、 Coactivator 、 Metastasis 、 Internal medicine 、 Epithelial–mesenchymal transition 、 Cancer research 、 Immunohistochemistry 、 Cadherin 、 Nuclear receptor 、 Cancer cell 、 Oncology 、 Adenocarcinoma 、 Surgery 、 Hematology 、 General Medicine
摘要: Background It was reported that the nuclear receptor coactivator amplified in breast cancer1 (AIB1) could regulate cancer cell invasion and migration a signaling-independent manner. Meanwhile, process of epithelial mesenchymal transition (EMT) is critical for tumor metastasis. The present study aimed to determine role AIB1 EMT markers human pancreatic adenocarcinoma.
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