Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction
作者： K. J. Pearson , K. N. Lewis , N. L. Price , J. W. Chang , E. Perez
关键词: Caloric theory 、 Internal medicine 、 Carcinogen 、 Insulin 、 Biology 、 Carcinogenesis 、 Regulation of gene expression 、 Enzyme 、 Cancer 、 Pharmacology 、 Oxidative stress 、 Endocrinology
摘要: … the differences seen in NQO1 mRNA levels (Fig. 1B). NQO1 activity was significantly increased in … Recent data from invertebrates suggested that Nrf2 or at least some of its downstream …
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