作者: Martin Ringwald
DOI: 10.1007/978-1-4615-2466-3_5
关键词: Cadherin 、 Morphogenesis 、 Cell adhesion molecule 、 Catenin complex 、 Cell sorting 、 Function (biology) 、 Cell biology 、 Adhesion 、 Adherens junction 、 Chemistry
摘要: Cadherins are a protein family of Ca2+-dependent transmembrane-type cell adhesion molecules. They mediate cell-cell by homophilic binding. All solid tissues in vertebrates express some Cadherins. Very importantly for their function, the different Cadherin subtypes show distinct developmental and tissue-specific patterns expression display corresponding binding specificities. In this way, thought to influence sorting, morphogenesis, maintenance adult (Takeichi, 1988, 1991; Kemler et al., 1989).