Transport of α-Aminoisobutyric Acid across Brain Capillary and Cellular Membranes

作者: Ronald G. Blasberg , Joseph D. Fenstermacher , Clifford S. Patlak

DOI: 10.1038/JCBFM.1983.2

关键词: MembraneCapillary actionBiochemistryChemistryAminoisobutyric acidDiethylenetriaminepentaacetic acidBlood–brain barrier

摘要: The transport of α-aminoisobutyric acid (AIB), N-methyl-AIB (MeAIB), and diethylenetriaminepentaacetic (DTPA) from blood to brain was measured over different experimental periods in eight regi...

参考文章(55)
WH Oldendorf, Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection American Journal of Physiology. ,vol. 221, pp. 1629- 1639 ,(1971) , 10.1152/AJPLEGACY.1971.221.6.1629
Joseph D. Fenstermacher, Ventriculocisternal Perfusion as a Technique for Studying Transport and Metabolism Within the Brain Research Methods in Neurochemistry. pp. 165- 178 ,(1972) , 10.1007/978-1-4615-7748-5_7
Dale L. Oxender, Halvor N. Christensen, DISTINCT MEDIATING SYSTEMS FOR THE TRANSPORT OF NEUTRAL AMINO ACIDS BY THE EHRLICH CELL Journal of Biological Chemistry. ,vol. 238, pp. 3686- 3699 ,(1963) , 10.1016/S0021-9258(19)75327-7
R. G. Blasberg, J. Gazendam, C. S. Patlak, W. S. Shapiro, J. D. Fenstermacher, Changes in Blood-Brain Transfer Parameters Induced by Hyperosmolar Intracarotid Infusion and by Metastatic Tumor Growth Advances in Experimental Medicine and Biology. ,vol. 131, pp. 307- 319 ,(1980) , 10.1007/978-1-4684-3752-2_24
Ronald G. Blasberg, Specificity of Cerebral Amino Acid Transport: A Kinetic Analysis Progress in Brain Research. ,vol. 29, pp. 245- 258 ,(1968) , 10.1016/S0079-6123(08)64160-6
Abel Lajtha, Jenö Toth, THE BRAIN BARRIER SYSTEM?III. Journal of Neurochemistry. ,vol. 9, pp. 199- 212 ,(1962) , 10.1111/J.1471-4159.1962.TB11861.X
C. S. Patlak, K. D. Pettigrew, A method to obtain infusion schedules for prescribed blood concentration time courses Journal of Applied Physiology. ,vol. 40, pp. 458- 463 ,(1976) , 10.1152/JAPPL.1976.40.3.458
Ernest M. Wright, Accumulation and transport of amino acids by the frog choroid plexus. Brain Research. ,vol. 44, pp. 207- 219 ,(1972) , 10.1016/0006-8993(72)90376-9
A. V. Lorenzo, R. W. P. Cutler, Amino acid transport by choroid plexus in vitro. Journal of Neurochemistry. ,vol. 16, pp. 577- 585 ,(1969) , 10.1111/J.1471-4159.1969.TB06857.X
H. Brent Clark, Boyd K. Hartman, Marcus E. Raichle, Sheldon H. Preskorn, Kenneth B. Larson, An intravenous technique for the measurement of cerebral vascular extraction fraction in the rat. Journal of Cerebral Blood Flow and Metabolism. ,vol. 2, pp. 187- 196 ,(1982) , 10.1038/JCBFM.1982.18